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Generic Name Omeprazole DrugBank Accession Number DB00338 Background. Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders.These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. When paying with Prime, select meds can be as low as $1/month. Free two-day shipping Get your medications delivered right to your doorstep with Amazon Pharmacy. Save at local pharmacies Need meds today? Use your Rx savings card for Prime prices at over 60,000 pharmacies. Learn more about Prime savings › Compare prices in seconds Prilosec OTC, Omeprazole Delayed Release 20mg for Heartburn, Acid Reducer, All Day, All Night*, Wildberry Flavor, 20mg, 14 Tablets. 412 4.7 out of 5 Stars. 412 reviews. Save with. Pickup Delivery 2-day shipping. Prilosec Otc Acid 20Mg Reducer Tablets - 42 Ea. Add. $31.98. current price $31.98. 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