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March 17, 2016. The U.S. Food and Drug Administration today issued a rule finalizing three previously-issued interim final rules designed to further reduce the potential risk of bovine spongiform. The one current VFD drug used in beef cattle, tilmicosin, will switch to the new rule on October 1, 2015. The OTC drugs used in or on feed will change to VFD drugs on January 1, 2017. In keeping with the FDA's theme of judicious use of medically important antimicrobials, pharmaceutical companies have voluntarily agreed to remove any growth. Increxxa TM (tulathromycin injection). Increxxa ™ contains tulathromycin, the same macrolide antibiotic veterinarians and the cattle industry have depended on to control and treat bovine respiratory disease (BRD) in cattle for more than 15 years. It's a go-to antibiotic for beef and dairy producers because of its one-time use, extended duration of action, ease of administration and broad. 183.25. USd/lb. -2.90 -1.56%. 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