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It is used for the treatment of dry cough. It helps by reducing the activity of the cough center in the brain. Benadryl DR Syrup can be taken with or without food. Take it whenever necessary or as prescribed by the doctor. Your doctor will decide how much you need to improve your symptoms. Benadryl Dosing Chart. Benadryl is an antihistamine. It comes in Children's liquid suspension, Children's Chewable tablets, Children's Meltaway strips or adult tablets. ** Take every 4 to 6 hours, or as directed by a physician. Do not take more than 6 doses in a 24 hour period. ** Do not use with any other products containing. Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side effect. 5. Tips. Benadryl may be taken with or without food. Take exactly as directed. Order Benadryl (Diphenhydramine) from Canada, at lower prices to the U.S. Available in . 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