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The maximum solubility of acyclovir in water at 37°C is 2.5 mg/mL. The pKa's of acyclovir are 2.27 and 9.25. Its empirical formula is C 8 H 11 N 5 O 3. The structural formula is provided in Figure 1: Dose: 5-10 mg/kg/dose IV q8h for at least 10 days; Info: may switch to PO antiviral after 2-7 days to complete course; may extend tx if not healed after 10 days. [recurrence] Dose: 400 mg PO tid x5 days; Start: ASAP after sx onset. [suppression] Dose: 400 mg PO tid; Start: 36 wk gestation. Acyclovir Acyclovir Ointment - 5% Ointment Source: Canada. Shipped from Canada. 5% - 4 g - Source: Canada - $72.95 5% - 30 g - Source: Canada - $499.95 Add to Cart How to Order Frequently Asked Questions Request Support Please note that due to government rules and regulations, orders may not exceed 3 months in supply. About this medication. ACYCLOVIR (ay SYE kloe veer) helps manage infections, such as cold sores and genital herpes, caused by viruses. 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