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XERESE ® (acyclovir and hydrocortisone) cream 5%/1% is a prescription medicine used in patients ages 6 and older to lessen the healing time of cold sores (herpes labialis) and lessen the chance of a cold sore becoming worse (ulcerating). It should be used early, at the first sign of a cold sore. Important safety information. XERESE is for cold sores on lips and around the mouth. Uses. This medication is used to treat " cold sores / fever blisters " (herpes labialis). It can speed up healing of the sores and decrease symptoms (such as tingling, pain, burning, itching. Acyclovir Acyclovir is a generic prescription version of the brand name drug Zovirax. It is used to manage symptoms of recurring (repeat episodes) oral or genital herpes. Acyclovir is also... CarePass™ price $14.79. Ships Free With. CarePassTM. or with $35+ orders. Out of Stock. FSA. Eligible. Abreva Docosanol 10% Cream Tube, FDA Approved Treatment for Cold Sore/Fever Blister, 2 grams On the Go Pack. Abreva. 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