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Aleve is available over the counter, so you can get long-lasting pain relief without a prescription. Anaprox ® is a. Finally, over the counter medications such as ibuprofen or naproxen may be prescribed to help provide relief from any pain or inflammation. If your symptoms persist or worsen, be sure to contact your healthcare provider to discuss the best treatment option.. In order to identify the exact cause of the pain, it is important to visit a doctor. A few medicines that you can get without a prescription (called over-the-counter or OTC medicines) can potentially increase seizures in people with epilepsy. They could even trigger a seizure for the first time. The most common OTC medicine that could do this is probably diphenhydramine, the active ingredient in medicines like Benadryl, which. Over-the-counter (OTC) painkillers are painkillers that you can buy without a prescription from a doctor. You may be able to buy them from a pharmacy or a shop. 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