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The European Commission has introduced a common logo that.Tramadol is a synthetic opioid and acts in the brain and spine (central nervous system) to reduce the amount of pain you feel. The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain. Tramadol is prescribed to treat moderate to severe pain. You may be prescribed tramadol to take regularly, or only when it is needed for pain relief. Make sure you know which is right for you. The most common side-effects are feeling sick (nausea) and feeling dizzy. In this article About tramadol Before taking tramadol How to take tramadol If you're 65 or over, or you have liver or kidney problems, your doctor may ask you to take tramadol less often. You can take your tramadol at any time of day but try to take it at the same time every day, and space your doses evenly. 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