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(1) age < 18 years (2) hypersensitivity to calcitriol or alfacalcidol (3) inadequate dialysis [defined as single-pooled Kt/V (sp-Kt/V) <1.2 and <2.0 for thrice a week and twice a week hemodialysis] (4) corrected serum calcium >10.2 mg/dL or serum phosphate >6 mg/dL after adjusting dialysate calcium and phosphate binders (5) diameter of. Calcitriol is a 1, 25-dihydroxycholecalciferol or a Vitamin D analogue. It increases the absorption of Calcium from intestine by forming a calcium binding protein. It reverses the signs of rickets and osteomalacia. Pharmacokinets of Calcitriol Absorption: It is readily absorbed after oral administration. Calcitriol and alfacalcidol are different than the vitamin D you can buy over-the-counter. Over-the-counter vitamin D needs to be activated by the kidneys in order to work in the body. People with kidney disease may not be able to do this kidney activation so we prescribe calcitriol or alfacalcidol, which already have the kidney activation done. Calcitriol is also used to treat calcium deficiency (hypocalcemia) and metabolic bone disease in people who are receiving dialysis. Calcitriol may also be used for purposes not listed in this medication guide. 000540007_PB. oval, yellow, imprinted with 547. 231550118_PB. After a single oral dose of 0.5 mcg Rocaltrol in healthy subjects, the average serum concentrations of calcitriol rose from a baseline value of 40.0 ± 4.4 pg/ml to 60.0 ± 4.4 pg/ml after two hours, and then fell to 53.0 ± 6.9 after four hours, to 50.0 ± 7.0 after eight hours, to 44 ± 4.6 after twelve hours and to 41.5 ± 5.1 pg/ml after 24 hours. Calcitriol 1Mcg 1Ml 25 Units'. 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