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Benadryl Ultratabs Antihistamine Allergy Medicine, 200 Tablets Diphenhydramine HCL 25 mg.Temporarily Relieves Runny Nose, Sneezing, Itchy or Watery Eyes and Itching of the Nose or Throat2 Bottles, 100 Tablets per Bottle The cost for diphenhydramine oral liquid (12.5 mg/5 mL) is around $11 for a supply of 118 milliliters, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies. 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