etomidate and succinylcholine order

This disclosure features compounds and compositions that are useful in methods of treating coronavirus infections (e.g., useful in methods of treating COVID-19) in a subject in need thereof. The methods include administering to the subject niclosamide compounds (or pharmaceutically acceptable salts and/or co-crystals thereof, e.g., niclosamide). Kienstra, AJ, Ward, MA, Sasan, F, et al. Etomidate versus pento-barbital for sedation of children for head and neck CT imaging. Pediatr Emerg Care 2004; 20: 499 - 506. CrossRef Google Scholar 12 Johnson, DM, King, RW, Bohnett, M. The safety and efficacy of etomidate as an adjunct to endotracheal intubation in the emergency department. "Succs" or Succinylcholine is a muscle relaxant. Etomidate is an anesthesia induction drug causing hypnosis. You never give Succs alone without Etomidate or some other drug for induction of anesthesia. Otherwise, you have a paralyzed patient with no hypnosis on board. For the most part, Succs does not effect cardiovascular numbers either. Medications for Rapid Sequence Endotracheal Intubation In order to achieve a successful intubation, various classes of medications are needed to achieve specific pharmacologic effects. These... Etomidate . 0.3 mg/kg, max 20 mg . Ketamine. 1 mg/kg, max 100 mg . Anticipate transient BP & HR . Lidocaine . 1 mg/kg, max 100 mg . ICP for head trauma, seizing . Relaxes airways in asthma . Lorazepam . 0.1 mg/kg, max 4 mg . Option for status epilepticus . Midazolam. 0.1 mg/kg, max 5 mg . Rocuronium. 1 mg/kg, max 100 mg . st 1 line paralytic. Etomidate vs Propofol-Induction Characteristics - Full Text View - ClinicalTrials.gov We're building a better ClinicalTrials.gov. Check it out and tell us what you think! Hide glossary Glossary Study record managers: refer to the Data Element Definitions if submitting registration or results information. Search for terms Accepts healthy volunteers Succinylcholine was more likely to produce excellent intubating conditions when using thiopental as the induction agent: RR 0.81 (95% CI: 0.73 to 0.88; n = 2302, 28 trials). Tients receiving etomidate (n = 62) versus succinylcholine (n = 213).14 In this trial, physicians were permitted to use etomidate with or without succinylcholine. When intuba-tion attempts failed after etomidate alone, rescue succinyl-choline was administered. Success rates for etomidate and succinylcholine intubations were 86.9% and 98.2%, respec- Etomidate and succinylcholine are used for RSI. The patient is started on a fentanyl and propofol infusion. Upon arrival at the tertiary care centre, with a systolic blood pressure of 140-160 mmHg throughout transfer.. This is premixed and is often part of a premedication given in order to avoid any hypotension during of after induction. Overall, twenty of the world's adult populations live with hypertension. Blood pressure determination forms an integral part of anesthesiologist's evaluation of the patient prior to and during surgery. 25% of surgical patients have hypertension preoperatively. There are several risks related to untreated preoperative hypertension in perioperative and postoperative phase. The. Etomidate is a non-barbituate, benzylimidazole general anesthetic agent. By far the most common use for etomidate in ICU patients is as an induction agent during rapid sequence intubation. Etomidate can also be used for deep sedation for procedures such as joint reduction or cardioversion, but this is most commonly done in the emergency department. Succinylcholine (Rx) Brand and Other Names: Anectine, suxamethonium, moreClasses: Neuromuscular Blockers, Depolarizing Print Dosing & Uses AdultPediatric Dosage Forms & Strengths injectable... Use of succinylcholine in neonates is surrounded by many controversies. The need to review this topic stems from the fact that though there is an abundance of information, but there are divergent views regarding its use in neonates. We have analyzed the incidence of intubation attempts, bradycardia, and hemodynamic changes in clinical settings.The authors conducted a meta-analysis and. The national recommendations of sedation concerning the intubation in emergency settings advise the use of a hypnotic, etomidate associated to succinylcholine. A national inquiry showed that more than 80% of prehospital intubations use a rapid sequence intubation as sedation. However, several recent studies throw into question the use of. Succinylcholine Dosage Applies to the following strengths: 20 mg/mL; 50 mg/mL; 100 mg/mL; 500 mg; 1 g; 100 mg/5 mL-NaCl 0.9%; 200 mg/10 mL-NaCl 0.9% Usual Adult Dose for: Anesthesia Usual Pediatric Dose for: Anesthesia Additional dosage information: Renal Dose Adjustments Liver Dose Adjustments Precautions Dialysis Other Comments McKesson Shop Products Shop by Category Manufacturer Diversity Etomidate does not have analgesic properties However, etomidate and succinylcholine produces less hypotension Hemodynamically stable, normotensive, well perfusing Option 1: 0.3 mg/kg etomidate PLUS 1.5 mg/kg succinylcholine Option 2: 2 mcg/kg fentanyl PLUS 2 mg/kg ketamine PLUS 1 mg/kg rocuronium Hypotensive or poorly perfusing 1. Triggers change in receptor that prevent agonist binding 2. Prevents activation of the receptor after it is bound by the agonist. A+C = increasing effect (response of receptor when bound) A+E = increasing affinity of receptor for drug A+B = decreasing affinity of receptor for drug A+D = decreasing effect (activation of receptor) La Succinylcholine - suxaméthonium est le curare dépolarisant d'action courte de référence en matière d'ISR à la posologie d'1. Ketamine/propofol admixture vs etomidate for intubation in the critically ill: KEEP PACE Randomized clinical trial. J Trauma Acute Care Surg, 87 (4) (2019), pp. 883-891. The evidence for use of tailored agents for specific clinical scenarios is very compelling and lends credence to expanding our repertoire beyond the traditional cocktail of etomidate and succinylcholine. References Walls R, Murphy M. Manual of Emergency Airway Management, 3rd ed. Lippincott Williams & Wilkins, 2008. Robinson N, Clancy M. McKesson Shop Products Shop by Category Manufacturer Diversity Etomidate does not have analgesic properties However, etomidate and succinylcholine produces less hypotension Hemodynamically stable, normotensive, well perfusing Option 1: 0.3 mg/kg etomidate PLUS 1.5 mg/kg succinylcholine Option 2: 2 mcg/kg fentanyl PLUS 2 mg/kg ketamine PLUS 1 mg/kg rocuronium Hypotensive or poorly perfusing 1. Triggers change in receptor that prevent agonist binding 2. Prevents activation of the receptor after it is bound by the agonist. A+C = increasing effect (response of receptor when bound) A+E = increasing affinity of receptor for drug A+B = decreasing affinity of receptor for drug A+D = decreasing effect (activation of receptor) La Succinylcholine - suxaméthonium est le curare dépolarisant d'action courte de référence en matière d'ISR à la posologie d'1. Ketamine/propofol admixture vs etomidate for intubation in the critically ill: KEEP PACE Randomized clinical trial. J Trauma Acute Care Surg, 87 (4) (2019), pp. 883-891. The evidence for use of tailored agents for specific clinical scenarios is very compelling and lends credence to expanding our repertoire beyond the traditional cocktail of etomidate and succinylcholine. References Walls R, Murphy M. Manual of Emergency Airway Management, 3rd ed. Lippincott Williams & Wilkins, 2008. Robinson N, Clancy M. The mechanism for adrenal suppression is inhibition of cortisol production. A single dose of etomidate can blunt adrenal function for up to 72 hours through inhibition of 11 beta-hydroxylase,... Laryngoscopy and intubation are uncomfortable; in conscious patients, a short-acting IV drug with sedative or combined sedative and analgesic properties is mandatory. Etomidate 0.3 mg/kg IV, a nonbarbiturate hypnotic, may be the preferred drug. Fentanyl 5 mcg/kg IV (2 to 5 mcg/kg in children; NOTE this dose is higher than the analgesic dose and. Indications. Succinylcholine chloride is a short-acting depolarizing neuromuscular blockade approved by the United States Food and Drug Administration (FDA) as a provision to other sedatives or hypnotics. It blocks the action of acetylcholine (ACh); hence, it disrupts all cholinergic receptors of the parasympathetic and sympathetic nervous systems. In reality, ordering the anti-epileptic drug from pharmacy, receiving it, and infusing it will often take ~20-40 minutes. Using the above algorithm, the levetiracetam will usually arrive from pharmacy after the seizure has already been controlled with propofol. The drug Etomidate is chemically identified as (R)- (+)-ethyl-1- (1-phenyethyl)-1H-imidazole-5-carboxylate and has the following structural formula: Molecular Formula: C 14 H 16 N 2 O 2 Molecular Weight: 244.3 Etomidate - Clinical Pharmacology Etomidate is a general anesthetic without analgesic activity. In order to quickly protect the airway, drugs with rapid onset such as etomidate, propofol, ketamine or thiopenthal are routinely used in combination with succinylcholine [5]. In elderly patients, etomidate is preferred, as it provides a greater haemodynamic stability compared to propofol or thiopental and more rapid emergence, while ketamine. `10. Dr Walker documented in her procedure note the use of Etomidate for sedation/ `analgesia and succinylcholine for neuromuscular blockade. `If he was already `unresponsive without reflexes, those medication would not have been needed. ` `11. Pulmonary edema (patient noted to have blood-tinged, frothy sputum) causes reduced `Exp C02. ` `12. Traditionally, succinylcholine is dosed 1—1.5 mg/kg and rocuronium is dosed 0.6—1.2 mg/kg. Succinylcholine generally takes 45—60 seconds for onset of laryngeal paralysis. When rocuronium is... Our doctors evaluate, diagnose, prescribe, order lab tests, and recommend follow-up care 24/7 Virtual Doctor Visits Connect in a minute Affordable with or without insurance Your health concern 0/250 Video chat with a U.S. board-certified doctor 24/7 in a minute. Orotracheal intubation is a life-saving procedure in critically ill patients with acute respiratory failure, but complications during the procedure are frequent and life-threatening situations still occur in almost 45% of the procedures (Simpson et al. 2012; Russotto et al. Trial protocol Supplement 2. . 15 ml Vernebler sowie Mundstück und T-StückLieferumfang:15 ml MedikamentenverneblerT.

can you buy nifedipine over the counter

Optimising efficacy and minimising cognitive impairment are goals of ongoing technical refinements.AimsTo compare the efficacy and cognitive effects of a novel electrode placement, bifrontal, with two standard electrode placements, bitemporal and right unilateral in ECT.MethodThis multicentre randomised, double-blind, controlled trial … Etomidate 0.3 mg/kg IV, or Ketamine 1-2 mg/kg IV Paralytic Succinylcholine 1.5 mg/kg IV, or Rocuronium 1 mg/kg IV Swanson and colleagues published data on RSI for patients in the aeromedical arena. In this study, etomidate was used on 53 of 79 patients (67%), with a success rate of 96%. Question In preparing a female client for electroconvulsive therapy (ECT), Nurse Michelle knows that succinylcholine. medications used include barbiturates such as thiopental and methohexital and nonbarbiturate agents such as propofol and etomidate. Seizure-induced by ECT should last longer than 30 seconds. Methohexital is the. 28 most. SIDE EFFECTS. The most frequent adverse reactions associated with use of intravenous etomidate are transient venous pain on injection and transient skeletal muscle movements, including myoclonus: Transient venous pain was observed immediately following intravenous injection of etomidate in about 20% of the patients, with considerable difference in the reported incidence (1.2% to 42%). The preference of etomidate together with a fast acting MR (succinylcholine or rocuronium) for RSI has been confirmed by many studies in emergency medicine, the last two involving children [ 160 - 170 ].Choi et al. [ 207] found that midazolam, even in low doses, often caused hypotension when used for RSI, in contrast to etomidate. O For the crashing hypotensive patient, we probably won't choose propofol. More commonly these days it seems that Etomidate is often used as it has one of the best hemodynamic profiles and still a relatively short time of effect. Paralytic Common meds here include Rocuronium, Succinylcholine, Nimbex, or Vecuronium. Again, these aren't always … When used for RSI iv the dose is 0.3. In hypotension or is the pulse rate us greater than the systolic blood pressure the dose of per Kg is halved from 0.3 to 0.15 mg/kg to prevent post induction hemodynamic instability. Etomidate can cause a myoclonic jerk which are a single gross limb movements. It has a rapid onset of 45 seconds. Background A nondepolarizing neuromuscular blocking agent (NMBA) with a succinylcholine-like quick onset and offset has been the holy grail of the science of neuromuscular blockade. Although this drug is still elusive, the advent of promising new drug combinations like rocuronium-sugammadex and gantacurium-l-cysteine may achieve the same end result. The type of NMBA; the type, timing, and. Ninety-six (19.2%) of a total of 499 patients received etomidate, with selection of induction agent left to provider discretion. Etomidate-treated patients responded less often to a corticotropin stimulation test than patients who did not receive etomidate (60.4% vs 43.4%, P = 0.004). A substudy of this trial explored the effect of etomidate. Only one arm in this study: patients who are treated with electroconvulsive therapy and have been given anesthesia with etomidate and succinylcholine. Procedure: ECT . ECT was administered twice a week with a constant-current brief-pulse device (Thymatron, System IV). Motor and electroencephalographic seizures were monitored to ensure adequate. It can also cause tachycardia, hypertension, and increased ICP if you don't! Etomidate Etomidate is the most common sedative that will be ordered for RSI intubation. Etomidate does not offer any analgesia, so sometimes fentanyl is added to minimize the SNS stimulation for patients with significant cardiovascular disease or increased ICP patients. Procedural sedation and analgesia (PSAA) is a more accurate and appropriate description. 5. PSAA produces a suppressed level of consciousness that is adequate to allow the administration of. Etomidate Injection, USP is a sterile, nonpyrogenic solution. Each milliliter contains Etomidate, 2 mg, propylene glycol 35% v/v. The pH is 6.0 (4.0 to 7.0). It is intended for the induction of general anesthesia by intravenous injection. The drug Etomidate is chemically identified as (R)- (+)-ethyl-1- (1-phenyethyl)-1H-imidazole-5-carboxylate. Etomidate Trade Name Amidate Etomidate Classification General Anesthetic. Is a hypnotic with no analgesic activity Etomidate Action Produces general anesthesia by augmenting the inhibitory tone of GABA on the CNS. Specific site of action is believed to be the reticular activating system. ETOMIDATE HAS NO ANALGESIC EFFECTS Etomidate Pharmacokinetics The Plants of Suncrest Nurseries. Suncrest Nurseries offers a decidedly offbeat plant collection aimed at enriching the California gardening experience. Geographically, we are focused on the Mediterranean-climate regions of the world—the Mediterranean area itself, Australia, South Africa, southern South America and most of all, California. We. Etomidate is a hypnotic agent used for the induction of general anesthesia and is commonly used for rapid sequence intubation (RSI). Medications used in RSI can contribute to hypotension after. Sometimes other agents are used for induction such as etomidate or ketamine,. receptor antagonists such as rocuronium or succinylcholine are used for this. The main difference between the two is that succinylcholine is a depolarizing agent - meaning that when it first binds to the ACh receptor,. Buy Swag. Study cards Christ A, Arranto CA, Schindler C, et al. Endotracheal intubation is done to: Keep the airway open in order to give oxygen, medicine, or anesthesia. The other parameters recorded were number of attempts required for intubation, duration of different stages of intubation,.It is called endotracheal intubation when the tube is inserted into the mouth and a nasogastric tube when the tube is fed. McKesson Log In; McKesson This item is refrigerated, and a $13.95 handling fee will be applied to your order. Learn more. Orders placed for this item cannot be canceled. Features. Specifications. Shipping. Reviews. Hospira's Quelicin ™ (succinylcholine chloride) comes in a multiple-dose glass fliptop vial. Concentration: 20mg/mL, 10mL vial. To study the association between the order of RSI medications and apneic time, researchers conducted a secondary analysis of a randomized, controlled trial comparing a bougie versus endotracheal tube and stylet for first intubation attempt.. Essentially all patients (>99%) received etomidate and 61% received succinylcholine. Providers. What is the best order of administration of medications? (a) Push rocuronium, then push ketamine. (b) Push ketamine, then push rocuronium. Defining time intervals in RSI Safe Apnea Time The safe apnea time is the amount of time that a patient will tolerate apnea, before developing critical hypoxemia. Chemical Name: Succinylcholine chloride, dihydrate Chemical Formula: C14-H30-Cl2-N2-O4.2H2O Contact Information: Sciencelab.com, Inc. 14025 Smith Rd. Houston, Texas 77396 US Sales: 1-800-901-7247 International Sales: 1-281-441-4400 Order Online: ScienceLab.com CHEMTREC (24HR Emergency Telephone), call: 1-800-424-9300 Etomidate 0.3 mg/kg IV, a nonbarbiturate hypnotic, may be the preferred drug. Fentanyl 5 mcg/kg IV (2 to 5 mcg/kg in children; NOTE this dose is higher than the analgesic dose and needs to be reduced if used in combination with a sedative-hypnotic, eg, propofol or etomidate) also works well and causes no cardiovascular depression. Etomidate Succinylcholine is on Facebook. Join Facebook to connect with Etomidate Succinylcholine and others you may know. Facebook gives people the power to share and makes the world more open and...

Malegra DXT cost

On the flight line we use roc instead of succ, and give the paralytic first. Because it has approx 60 second onset time, while etomidate is much quicker, giving roc first allows the effects of the roc and the etomidate to hit at the same time. That being said, with a crash airway I wouldn't wait the 60 seconds and would just drop a tube. Published: Jan. 30, 2023 at 4:38 a.m. ET. The MarketWatch News Department was not involved in the creation of this content. Jan 30, 2023 (The Expresswire) -- Global " Etomidate Injection Market. Material Name: Succinylcholine Chloride Injection, USP (Quelicin(TM)) (Hospira Inc.) Trade Name: Succinylcholine Chloride Injection (Quelicin(TM)) Chemical Family: Not determined Relevant Identified Uses of the Substance or Mixture and Uses Advised Against Intended Use: Pharmaceutical product Details of the Supplier of the Safety Data Sheet 2. Etomidate and rocuronium have become increasingly popular for the sedation and paralysis, respectively, of pediatric patients in rapid sequence intubation, and there are many advantages to the use of both agents. Both etomidate and rocuronium have a rapid onset of action, and both agents are relatively free of hemodynamic adverse effects. Etomidate Ketamine Barbiturates Opioids Lidocaine Neuromuscular blocking agents (NMBAs) Succinylcholine Defasciculation Alternatives to succinylcholine Nondepolarizing NMBAs Remifentanil intubation MASK VENTILATION Modified RSII CHOICE OF LARYNGOSCOPE POTENTIAL COMPLICATIONS OF RSII Difficult or failed airway Hypoxia Hypotension Regurgitation Etomidate (0.2-0.3 mg/kg IV) is another option, although some studies show negative outcomes in trauma patients. No dose reduction is needed in patients with shock or elderly patients, and 0.3... Conclusion: The use of fentanyl, as a co-induction agent with etomidate and succinylcholine during RSI, allows a significant delay of the awakening signs arrival and attenuate the neurovegetative response during the minutes after endotracheal intubation after RSI, without deleterious haemodynamic effects. Publication types Clinical Trial The safety of succinylcholine is limited by these relatively sensitive patients, and interestingly, a decrease in dose does not have a marked effect on the upper range of duration (10, 10.5, and 11 min in Kopman et al. 's study 3for 0.4, 0.6, and 1 mg/kg, respectively). Terms in this set (144) In which order should the paramedic typically assess for immediate threats to a patient's life? airway, breathing, circulation A drop in blood pressure of greater than 10 torr during inspiration is called: pulsus paradoxus. Physiologically, the term respiration refers to the: exchange of gases at the cellular level. Suggestion - Adequately prepare the patient for tracheal intubation, including pre-oxygenation, monitoring, and INTUBATION AND TRACHEOSTOMY appropriate positioning during the procedure in order to achieve optimal laryngoscopy. (32,33) Techniques for elective, semi-elective and emer- Suggestion - A curved-blade laryngoscope of the gency intubation … Anesthetic management of morbidly obese patients has to be carefully planned, in order to minimize the increased risks of aspirative pneumonitis, hemodynamic instability and delay in recovery.The ideal anesthesia should provide a smooth and quick induction, allowing rapid airway control, prominent hemodynamic stability, and rapid emergence from … Fc-smoke">Apr 15, 2021 · Brown 3rd CA, Walls RM. The intubation process helps in air passing inside and out in the lungs. . Intubation or ventilator use is defined by at least one of the following: Ventilator use is defined by any listed International Classification of Diseases, 10th Revision, Procedure Coding System (ICD-10-PCS) procedure codes: 5A19054, 5A1935Z. Succinylcholine can cause a rapid increase in intraocular pressure due to effects on ocular blood vessels & myofibrils. It can cause cardiac arrhythmias (increase or decrease in heart rate) because of its effects on muscarinic receptors and nicotinic-ganglionic receptors. There is an increased risk for potentially fatal malignant hyperthermia. The objective was to compare rates of successful endotracheal intubation (ETI) and requirement for multiple ETI attempts in patients receiving etomidate (ETOM) versus succinylcholine (SUX). This retrospective study analyzed adults in whom oral ETI was attempted by a helicopter EMS (HEMS) service between July 1997 to July 1999. Data were from records of the HEMS service, which uses a RN/EMTP. Expert Answers: Intubation is required when general anesthesia is given. The anesthesia drugs paralyze the muscles of the body, including the diaphragm, which makes it impossible Recent studies have shown no difference in usage of ketamine versus etomidate, and rocuronium versus succinylcholine in intubation conditions and first pass success in the Emergency Department Ultimately, the ketamine and rocuronium combination has equal efficacy and a superior safety profile in comparison to etomidate and succinylcholine. About Products and Service Guidechem will help you find Etomidate EP Impurity C 792842-51-4 suppliers from 0 different countries and regions around the world,1 products, both certified manufacturers and traders. You can choose and inquire according to your actual needs. Guidechem provides you with information matching service. If you have not found the right supplier, release the purchase. You reply, "Let's use succinylcholine, it has a faster onset." But does it? Traditionally, succinylcholine is dosed 1—1.5 mg/kg and rocuronium is dosed 0.6—1.2 mg/kg. Succinylcholine What is used as adjunct (Loading Dose) for propofol Midazolam Major IV GA thiopental etomidate propofol ketamine midazolam Classes of PRe-Anethetic Meds BZD and Barbiturates Opiod Analgecs Antihistamines APs Neuromuscular blockers Anticholinergics Antiemetics Antacids BZD pre anesthetics

fartolin buy

Normal adults. The box on the lower right-hand side of the graph depicts time to recovery from succinylcholine, which in almost all cases exceeds safe apnea time. Note also the precipitous decline of oxygen saturation from 90% to 0% for all groups. (Modified from Benumof J, et al: Critical hemoglobin desaturation will occur before return During the normothermic (35.8 °C) cardiopulmonary bypass, the heavily calcified, stenotic tricuspid aortic valve was replaced with a biological 23 mm Edwards Perimount Magna Ease Aortic valve prosthesis via partial medial sternotomy. The cardiopulmonary bypass time and the cross-clamping time were 134 min and 96 min, respectively. Succinylcholine (60-90 seconds) Neostigmine cholinesterase inhibitor used to reverse non-depolarizing paralytics Side Effects of succinylcholine Hyperkalemia; raises ICP; vagal; histamine release Most common Rapid Sequence Induction drugs Etomidate and Succinylcholine Train of Four A technique used for monitoring level of paralysis If you had known it was succinylcholine, then you would have given a non- depolarizing muscle relaxant, and this problem would never have occurred. Reference 1.Collins JS, Lemmens HJM, Brodsky JB, Brock-Utne JG, Levitan RM. Laryngoscopy and the morbid obesity: a comparison of the "sniff" and "ramped" positions. Obes Surg. 2004;14:1171-5. MauricefiA etal Open 2199e24249 doi11136/bmopen2124249 1 Open access GASS Trial study protocol: a multicentre, single-blind, randomised clinical trial comparing general anaesthesia and sedation during intra- AMIDATE (Etomidate Injection, USP) is a sterile, nonpyrogenic solution. Each milliliter contains etomidate, 2 mg, propylene glycol 35% v/v. The pH is 6.0 (4.0 to 7.0). It is intended for the induction ofRead more Did you find an answer to your question? Yes No CLINICAL PHARMACOLOGY Etomidate is a general anesthetic without analgesic activity. Intravenous anesthetics are a group of fast-acting compounds that are used to induce a state of impaired awareness or complete sedation. Commonly used intravenous anesthetics include propofol, etomidate, ketamine, and barbiturates (e.g., thiopental). Propofol is the standard drug for induction of anesthesia and etomidate is most commonly used in cases of hemodynamic instability. Competitive acetyl choline (ACh) receptor antagonists such as rocuronium or succinylcholine are used for this. The main difference between the two is that succinylcholine is a depolarizing agent - meaning that when it first binds to the ACh receptor, it causes a contraction, whereas rocuronium is non-depolarizing - so when it binds nothing. Etomidate 0.3 mg/kg IV 70kg = 14 - 20 mg <1 minute 3-5 minutes Adrenal insufficiency Septic shock? BP effect minimal No analgesia Myoclonus possible. Succinylcholine Depolarizing agent 1-1.5 mg/kg IV (TBW) 70kg = 70-100 mg (3-4 mg/kg IM emergency) 30-60 seconds 10-15 minutes K > 5.5 Malignant hyperthermia hx Succinylcholine Dosage and Route Route: IV, IM Dosages: Adult: 1-1.5 mg/kg IVP or 2.5-4.0 mg/kg IM. Maximum dosage 150 mg Repeat once if needed Pediatric: 1-1.5 mg/kg IVP or up to 2 mg/kg IM. Maximum dosage 150 mg Repeat once if needed, use 2 mg/kg in infants (patients 0-12 months) Etomidate Classification