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Special Instructions: strength 100 mg levodopa and 25 mg carbidopa, Increase by 1 tablet every other day until a dose of 8 tablets is reached. Geriatric. Disease: Parkinson's Disease. Before or After Meal: Either. Single Maximum Dose: 1 Tablet. Dosage Form: Tablet. Dosage Route: Oral. Carbidopa/levodopa is the mainstay of treatment for PD and is the most effective medication available for PD. APDA research funding played a role in the discovery of levodopa for PD treatment, when we funded the work of Dr. George C. Cotzias back in the 1960s. The lowest price on PharmacyChecker.com for Sinemet (carbidopa-levodopa) 10 -100 mg is $0.73 per tablet for 300 tablets at PharmacyChecker-accredited online pharmacies. Lowest U.S. Pharmacy Coupon Price: $1.04 per tablet for 300 tablets. Lowest International Mailorder Pharmacy Price: $0.73 per tablet for 300 tablets. 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Available Doses: 4.86/20 per mL Typical Treatment Regimen: Up to 2,000 mg of. Carbidopa/levodopa: Dosing, contraindications, side effects, and pill pictures - epocrates online Find medical information for carbidopa/levodopa on epocrates online, including its dosing, contraindications, drug interactions, and pill pictures. Drugs Diseases Interaction Check Pill ID Calculators Tables Guidelines CMENew Login Advanced Parkinson's Disease: Most common adverse reactions (incidence ≥ 5 % and greater than oral immediate-release carbidopa-levodopa) are nausea and headache. Postmarketing Experience: Reported adverse reactions identified during post approval use of RYTARY include suicide attempt and ideation. Because these reactions are reported. 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