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Doctors seeking to join our worldwide list of Doctors, may send mail. The most commonly used medicine for type 2 diabetes, metformin, also seems to extend the lifespan of many small animals, including mice, by around 5 per cent. There have been no trials of...
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There are many indications of metformin's life-extending potential: Metformin activates AMPK, the same autophagy pathway activated by exercise, fasting, polyphenol consumption, and reduced calorie intake. Metformin also seems to protect against many of the conditions that kill people, like cancer. Novel regulators of life extension by metformin are also presented. Highlights The diabetes drug metformin is to be clinically tested in aged humans to achieve health span extension, but little is known about responses of old non-diabetic individuals to this drug. Life extension is the concept of extending the human lifespan, either modestly through improvements in medicine or dramatically by increasing the maximum lifespan beyond its generally-settled limit of 125 years.. Several researchers in the area, along with "life extensionists", "immortalists" or "longevists" (those who wish to achieve longer lives themselves), postulate that future. 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He is confident that the results will forever alter the way we launch and trial longevity medications in the future.
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